African American History Essay Example | Topics and Well Written Essays - 500 words - 2

African American History - Essay Example Due to industrialization, the north comprised of educated people both blacks and whites (Morgan, 68). As a result of the differences in northern and southern economies, perceptions about slavery also differed between the two economies. According to Morgan (68), the northern whites worked alongside the blacks in the industries and the blacks were not subjected to degradation. Some whites owned slaves who worked in farms and houses and one could buy his/her freedom. On contrary, the southern slaves did not mix with whites; they were slave societies. The African-American slaves were considered inferior to the whites hence subjected to hard work under poor working conditions. The northern was religious and believed in the unalienable rights of all human beings. Slavery was thus abolished in the north and all slaves freed. However, even after the emancipation proclamation by Lincoln, the south used Ku Klux Klan to maintain white supremacy; the blacks were denied the right to vote as they were inferior race. However, both the south and the north agreed that they were more superior since t hey were more educated and due to their color (Duiker & Spielvogel, 497-498). Frederick Douglass is considered the father of integration. He advocated for the abolition of slavery in America and believed in the virtues entailed in the declaration of independence; right to life, liberty and pursuit of happiness (Myers, 2011). He also believed that the blacks could enjoy the rights, privileges and immunities that were enjoyed by the whites. He advocated for self-elevation or self-sufficiency to be able to acquire the same status as the whites. For him, dependency on the whites was out of question. The blacks needed education in order to be at the same level as the whites hence he advocated for removal of segregation in schools. All human beings are equal, hence the whites and the blacks could perform same tasks, have same rights of voting

Evaluate the proposition that the research findings from the use of Essay

Evaluate the proposition that the research findings from the use of animal models has led to new approaches to reduce the effects of ageing in wound healing - Essay Example This might help to identify the targets for novel and effective drug therapy. Normal wound healing is innate host immune response for tissue regeneration and repair involving coagulation, inflammation, epithelialization, formation of granulation tissue and tissue remodeling (Ashcroft et al. 2002). In response to injury stages of wound healing are depicted in figure 1 (Gosain and DiPietro 2004). The number of polypeptide growth factors and cytokines like epidermal growth factor (EGF), basic fibroblast growth factor (ÃŽ ²-FGF), platelet derived growth factor (PDGF) A & B isoforms, the transforming growth factor (TGF-ÃŽ ²), vascular endothelial growth factor (VEGF) plays an important role in wound healing process. It is demonstrated that delayed wound healing in both elderly animal and human individuals is due to decreased inflammatory and proliferative responses, delayed angiogenesis, delayed remodeling and slower reepithelialization (Strigini and Ryan, 1996). Morphology of skin changes with aging process. It involves flattening of the dermo-epidermal junction, disorganized microcirculation, decrease in number of cells as well as dermal cell constituents like fibroblasts, mast cells, macrophages. Also, the morphology, properties and quantity of dermal extracellular matrix content such as collagen, elastin, glucosaminoglycans changes with aging. These variations lead to delayed cellular proliferation, migration, modified binding of growth factor to matrix, alteration in adhesion molecule synthesis and changes in molecular signaling (Ashcroft et al. 2002). These changes affect functional cell response to all the stimuli. The age-related changes in the individual phases of healing are summarize d in Table 1 (Goain and DiPietro 2004). The animal models which are used to study the impact of aging on wound healing are not suitably characterized. Therefore the reported evidences itself are contradictory (Ashcroft et al., 1995). Only well